5 Best Aquarium Bacteria Supplement For Fish Tank

How do you know if your aquarium needs a bacteria supplement? Some signs that you might need a bacteria supplement are cloudy water, algae growth and fish stress. If you have noticed any of these things in your tank it is time to take action by adding the best aquarium bacterial supplement for your fish tank. There are many different types of products available on the market today but we can help narrow down your search with our list below!

Best Aquarium Bacteria Supplement For Your Aquarium

Instant Ocean BIO-Spira Water Treatment for Aquariums

The Instant Ocean Bio-Spira water treatment is an excellent way to turn any new aquarium into an established aquarium immediately! The specially blended bacteria in this product make it easy for a tankโ€™s bio filter to get started and also speeds up the running time of your protein skimmer. It is great for tanks that have just finished setting up as well as after adding new fish or medicating them. Simply add 2 capsnups of this product once per day when filling the tank with fresh salt water, on days where you will be giving your fish medication use 1 capsnup.

Instant Ocean BIO-Spira treats up to 75 gallons of water in marine aquariums. This powerful additive is shelf stable and does not require refrigeration so you can treat your tank on the go. The 250ml bottle includes a one step, stand-alone treatment that creates a complete ecosystem for aquacultures without icky chemicals or complicated math!

The Aquaculture Revolution is Now Simple: Instant Ocean BIO-Spira adds all necessary bacteria, iodine, chlorine, copper in just 3 easy weeks!

DrTim’s Aquatics Reef


One & Only from DrTimโ€™s Aquatics quickly converts aquarium waste in marine tanks to a non-toxic form. Utilize this powerful solution when setting up new fish tanks, while cleaning filters or adding new fish or after a water change. Removes harmful toxins from reef, nano and seahorse aquariums with regular water changes and coral refugiums that depend on healthy bacteria growth for ongoing success.

Your new aquarium needs a thorough and proper clean-out to make it safe for your fish. One & Onlyโ€™s DrTim’s Aquatics Reef is 100% natural, with no harsh cleaners that could harm either you or your pet aquatic life.

This product can be purchased in various quantities including 2 ounces on up to 128 ounces, perfect for stocking up the first time you order this all-natural cleaner made by industry expert DrTim himself! It contains nothing but pure ingredients like baking soda, essential oils, and lemon juice – organic items which keep your animals happy and healthy so they thrive without being exposed to chemicals.

API Quick Start Nitrifying Bacteria


API QUICK START Freshwater and Saltwater Aquarium Nitrifying Bacteria 16-Ounce Bottle helps to reduce the toxic compounds within fish tanks when used regularly. With just a dose of this bacteria, you can add an entire tank’s worth of fish to your ecosystem.

The API team puts over 40 years of experience into every bottle at no extra cost so you can save time while saving the planet from pollution.

The Quick Start Nitrifying Bacteria is the easy answer for setting up a new aquarium with an abundance of good bacteria. It’s designed to help prevent fish loss caused by poor conditions, such as ammonia and nitrite toxicity. Simply sprinkle on top a thin layer of this probiotic supplement and observe the remarkable transformation in your tank environment over time! You’ll notice vibrant colors in your plant life, clearer water quality, less algae growth and rapid development of the rich marine community that lives within it. And dolphins give you high-fives! Get some now!

Seachem Stability Fish Tank Stabilizer


Younger families often have a lot of energy, and the best way to channel it is into an aquarium. Younger kids typically like sitting on hard floors or laps, and older ones might want to ride around on furniture. With Seachem Stability Fish Tank Stabilizer you can put away your worries about whether that new addition to your family will inadvertently kill off those loved fish.

Plus, if you’re tired of too many choices for dinner when trying to prepare food for the family, try cooking in bulk so everyone can share their favorite foods with one another โ€“ including seafood! With Stability’s nutrient-rich bacteria – perfect for sealing protein as well as catering specifically towards different pH levels.

Seachem Stability is used for established aquariums in need of a quick fix. A steady environment with plenty of oxygen can create stability, but any sudden change to the environment can include high parameters for pH, salinity, temperature and more. This poses a danger to your aquatic pets that may have built up tolerance over time. Excess waste and depletion will cause these environments to become uninhabitable which is why you should only use Stability as needed when introducing new fish or aquatics plants into your tank. Seachem Stability – it’s not just one thing that helps keep everything stable, it’s every little detail! Always be prepared with this handy bottle on hand for emergencies when it seems like the whole world has gone crazy!

Fluval Cycle Biological Enhancer


Whatโ€™s cycling your aquarium but not really getting anything done? Fluval Cycle Biological Enhancer is pH balanced and contains ammonia’s natural enemy, nitrite. It immediately establishes the safe biological environment needed for an active freshwater or saltwater aquarium by eliminating unwanted ammonia and nitrite. It’s a powerful solution for strong cycle support that responds to changing water conditionsโ€”a perfect choice for many of your aquatic needs.

Light enough to break through the cloudy haze in your tank, it packs quite a punch as you watch silicates reduce bacterial blooms while also smoothing down any rough edges on rock surfaces with its infinite softness. Your next big cleaning job just got easier; save time and money with Fluval Cycle Biological Enhancer!

The Fluval Cycle Biological Enhancer is a new and innovative way to keep your aquarium healthy. Nearly 20% of fish go without ever being detected when they are sick, leading them to die from things that could be prevented through early detection. No one wants their beloved pet fish to waste away because they werenโ€™t able to save them from what might have been something as simple as a parasiteโ€ฆ in fact, the day old use for this product will change how you look at your tank maintenance forever!

Nutrafin Cycle Biological Filter Supplement


Nutrafin Cycle Biological Filter Supplements are fast-acting responsive ammonia and nitrite elimination. Consistent performance from each container due to bio-floc technology for improved shelf life and product viability. This filter supplement’s biologically active ingredients provide consistent quality and reliability for this all in one water purification system that doesn’t need extra items like carbon, vacuum pumps, salt, or other chemicals. The Nutrafin Cycle Biological Filter Supplement is easy to use with clear installation instructions on back of bottle for replacing the filter every 6 months without complication.

Each bottle of Nutrafin Cycle Biological Filter Supplement contains enough liquid to treat up to 30 gallons (or 223 L) for one month. Made from carefully selected natural and proprietary ingredients, it quickly eliminates biological pollutants that can be destructive to the ecosystem inside your aquarium. Packaged in amber glass with a non-vented cap, this product is predisposed to UV light degradation over time meaning that contents should be taken out of sunlight as soon as possible after purchase and before adding water. Safe for fresh or saltwater tanks Fedex ground delivery if you’re not close by!

How to choose Best Aquarium Bacteria Supplement

1. Product Shelf Life:

Choose a bacterial supplement that’s been around for a long time and has had positive reviews from customers. A product may be popular, but if you can’t tell how long it’s been on the market , or if there isn’t an expiration date listed on the packaging then chances are it doesn’t have much of a shelf life.

2. Tank Size

The size of the tank is another important factor when choosing a bacterial supplement for your fish tank. A famous fish product manufacturer can enter into the market with certain bacteria products to keep tanks clean and healthy, but they only work efficiently in a specific size or range . So, it’s better for you to check what kind of aquarium vessels are supported by the product you want to buy.

3. Type of Starter

When you buy a bacterial supplement, make sure it’s the one that comes with a starter or not. A starter is fish food for bacteria and the magic powder can’t grow without it. So if you won’t get a starter, ask your seller about how to use it and how to help the bacteria grow without a starter.

4. Price:

An average price of fish tank bacteria supplement is between $5 and $10. You can buy it from online stores or your local pet shop, but be sure that you get the right one for your tank size because if you do not pay attention to this detail, you will end up with a bottle of useless bacteria product.

Knowing When to Add Bacteria Supplements

1. Cycling a New Aquarium:

Cycling an aquarium can take from two to eight weeks, depending on the number of fish and other factors. Start by adding small amounts of live bacteria or ammonia remover into the water before releasing any fish or putting in a substrate (such as gravel). The cycling process is complete when your tank’s filter produces 0.5 to 1.0 ppm of ammonia on a consistent basis.

2. Adding New Fish:

Ensure the cycling process is complete before adding new fish. Do not add more than five fish for every 10 gallons of water in your tank, and do not put in any additional fish until you are sure your aquarium has enough bacteria to prevent ammonia and nitrite spikes.

3. Water Changes:

Always do a 50 percent water change at least once every two weeks. Water changes remove harmful toxins and replenish beneficial bacteria that aid in breaking down fish waste.

4. Medicating Your Fish:

If you need to medicate your fish, always do a large water change before and after medicating your aquarium. This will get rid of any harmful toxins as well as the medication itself. Be sure to remove any carbon filters from your tank during medication use so they don’t absorb medications or other chemicals from the air that can be fatal for fish. When using copper medication, remember to turn off UV sterilizers as these may consume copper ions until they are exhausted, which could possibly harm your plants and especially invertebrates such as shrimp and snails if not removed when no longer needed.


1. Why use conditioners and bacteria together?

The conditioner washes away all the fish waste for you, so your bacteria does not have to compete with it. The more food that is in the water, the faster your bacteria will grow and multiply.

2. How long will the bacteria live?

If stored properly (with a light dusting of mineral oil), then almost indefinitely! If they are exposed to air for any length of time they will die, however – so be sure to keep them under mineral oil at all times. And make sure you buy only UV protected glass containers which prevent harmful ultra-violet light from reaching the capsules or tabs inside!

3. How do I store the bacteria supplements?

Some people prefer to pop open the capsule and pour the beads out into a bottle. But that’s not necessary if you simply keep the capsules stored in their original containers filled up with mineral oil, and then wipe off any excess each time you remove some for treating your tank.

4. Is Aquarium Bacteria Safe?

Yes – absolutely! Anyone who suggests otherwise is either misinformed or trying to sell you something! It’s very important to understand that this bacteria has no effect at all on creatures other than fish, so there is no danger of it harming anything except certain species of fish parasites (which are far smaller than typical aquarium fish). In fact, this is why almost all commercial hatcheries use Bio-Spira as their first step after hatching baby carp – since it can aid in preventing the spread of these parasites as well as helping keep the baby fish healthy through their first few months until they are large enough to defend themselves.


The best aquarium bacteria supplement can often be found in the form of a live culture. This is because it contains natural pro-biotics and probiotics that are needed to maintain an optimal balance for your fish tank. There are many different brands available, so you should do your research before making a purchase decision. Memfish recommend looking at reviews from other customers who have had experience with this type of product or using our helpful buying guide below!